Search on: PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1 
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Descriptor English:   Protein Tyrosine Phosphatase, Non-Receptor Type 1 
Descriptor Spanish:   Proteína Tirosina Fosfatasa no Receptora Tipo 1 
Descriptor Portuguese:   Proteína Tirosina Fosfatase não Receptora Tipo 1 
Synonyms English:   PTPase 1B
PTPase HA2
Protein Tyrosine Phosphatase 1B
Protein-Tyrosine Phosphatase HA2
Protein Tyrosine Phosphatase HA2
Protein Tyrosine Phosphatase, Non Receptor Type 1  
Tree Number:   D08.811.277.352.650.775.300.100
D12.644.360.585.100
D12.776.476.564.100
Definition English:   A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52696 
Unique Identifier:   D054562 

Occurrence in VHL:
 

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